Skip to main content
. 2024 Sep 3;20(9):e1011864. doi: 10.1371/journal.ppat.1011864

Fig 7. Protein Structure model divergence predicted by alphafold2 and aligned and visualized in PyMol 2.55 for the nucleoprotein gene of filoviruses and filovirus-like sequences in vertebrate genomes.

Fig 7

A. Purple cartoon indicates the predicted the structure from the NP-like open reading frame sequence of Nannospalax (African mole rat; predicted template modeling score, pTM = 0.83) and green cartoon represents the predicted structure of NP from TAPV (assembled from a lancehead snake, pTM = 0.87) B. Blue cartoon indicates the predicted the structure from the NP-like open reading frame sequence of XILV (a fish-associated filovirus, pTM = 0.77) and the green cartoon represents the predicted structure of NP from TAPV (assembled from a lancehead snake). C. Multidimensional Scaling plot of root mean squared deviations (RMSD) of predicted protein structure of the Nucleoprotein NP from filoviruses and filovirus-like sequences in vertebrates after alignment in PyMol. Ovals indicate major clades found in the phylogenetic analyses presented here. Red shaded stimuli are based on viral structures while blue stimuli are predicted from vertebrate genome sequences. Solid shading indicates extended open reading frames are present.