Table 2.
Rates of events with confidence intervals according to smoking intensity
| Diagnostic results | Complications | |||||||
|---|---|---|---|---|---|---|---|---|
| Pack-year | Diagnosis of malignancies | Non-diagnostic pathologies | False-negative results in non-diagnostic pathologiesa | False-negative results in non-specific benign pathologiesa | Pneumothorax | Pneumothorax requiring drainage catheter | Hemoptysis | |
| Total | Rates | 65.4% | 27.5% | 20.5% | 13.0% | 21.8% | 2.1% | 10.6% |
| 95% CI | 64.0–66.8% | 26.2–28.8% | 18.2–22.9% | 11.0–15.3% | 20.6–23.0% | 1.7–2.5% | 9.7–11.5% | |
| 0–20 | Rates | 63.0% | 28.6% | 16.4% | 9.7% | 19.4% | 1.4% | 13.2% |
| 95% CI | 61.2–64.7% | 27.0–30.3% | 13.9–19.2% | 7.5–12.1% | 18.0–20.9% | 1.0–1.9% | 12.1–14.5% | |
| 21–40 | Rates | 68.1% | 25.3% | 25.5% | 18.8% | 25.5% | 2.3% | 6.4% |
| 95% CI | 65.0–71.1% | 22.5–28.2% | 19.8–31.9% | 13.3–25.5% | 22.7–28.5% | 1.4–3.5% | 4.9–8.2% | |
| > 40 | Rates | 72.4% | 25.2% | 33.3% | 23.0% | 27.2% | 4.8% | 4.8% |
| 95% CI | 69.0–75.7% | 22.1–28.6% | 26.1–41.2% | 16.0–31.4% | 23.9–30.6% | 3.3–6.6% | 3.3–6.6% | |
| Pairwise comparisonb | 0–20 vs. 21–40 | 0.005 | 0.05 | 0.003 | < 0.001 | < 0.001 | 0.06 | < 0.001 |
| 0–20 vs. > 40 | < 0.001 | 0.07 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |
| 21–40 vs. > 40 | 0.06 | 0.97 | 0.10 | 0.38 | 0.45 | 0.005 | 0.16 | |
Abbreviations: CI confidence interval
a From non-diagnostic pathologies or non-specific benign pathologies with decidable reference standards
b If p value is less than 0.05/3 (= 0.0167), it was thought to be statistically significant