Table 1.
Attribute (not shown) | Label | Levels |
---|---|---|
Mode, frequency, and location of administration | How the medication is taken | Injected under the skin of the abdomen once a month at a doctor's office [10, 39] |
Injected into the muscle of the arm, thigh, or buttock once every 3–4 months at a doctor's office [10, 38] | ||
Injected into the muscle of the arm, thigh, or buttock once every 6 months at a doctor's office [10, 38] | ||
Pill taken daily at home [9, 10] | ||
Testosterone surge within the first few days of administration, which can be treated with additional medication | Additional medication is needed to prevent a testosterone surge from occurring | Additional medication (a pill) is needed to prevent a testosterone surge; taken daily for approximately 3 weeks to prevent a testosterone surge from occurring [2] |
The treatment does not cause a testosterone surge, so no additional medication is needed [24] | ||
Impact on sexual interest | Decreases interest in sex | Decreases interest in sex very much [11] |
Decreases interest in sex moderately [36] | ||
Decreases interest in sex a little [37] | ||
Risk of cardiovascular events | X out of 100 men (X%) taking the treatment have a heart event (such as a heart attack or stroke) | 3% [24] |
6% [24] | ||
Percentage of patients achieving normal testosterone after 3 months | 3 months after stopping treatment, X out of 100 men (X%) will return to normal testosterone levels, meaning a reduction in treatment-related side effects, like hot flashes, fatigue, and sexual problems | 3% [24] |
16% [11] | ||
54% [24] | ||
Out-of-pocket cost | Total out-of-pocket cost for treatment, including all doses, is $X/montha | $5 |
$75 | ||
$200 | ||
$350 |
aThe levels of this attribute were not obtained from the literature, although they were evaluated in the cognitive interviews