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. 2024 Aug 21;41(10):3934–3950. doi: 10.1007/s12325-024-02955-1

Table 1.

Discrete choice experiment attributes and levels

Attribute (not shown) Label Levels
Mode, frequency, and location of administration How the medication is taken Injected under the skin of the abdomen once a month at a doctor's office [10, 39]
Injected into the muscle of the arm, thigh, or buttock once every 3–4 months at a doctor's office [10, 38]
Injected into the muscle of the arm, thigh, or buttock once every 6 months at a doctor's office [10, 38]
Pill taken daily at home [9, 10]
Testosterone surge within the first few days of administration, which can be treated with additional medication Additional medication is needed to prevent a testosterone surge from occurring Additional medication (a pill) is needed to prevent a testosterone surge; taken daily for approximately 3 weeks to prevent a testosterone surge from occurring [2]
The treatment does not cause a testosterone surge, so no additional medication is needed [24]
Impact on sexual interest Decreases interest in sex Decreases interest in sex very much [11]
Decreases interest in sex moderately [36]
Decreases interest in sex a little [37]
Risk of cardiovascular events X out of 100 men (X%) taking the treatment have a heart event (such as a heart attack or stroke) 3% [24]
6% [24]
Percentage of patients achieving normal testosterone after 3 months 3 months after stopping treatment, X out of 100 men (X%) will return to normal testosterone levels, meaning a reduction in treatment-related side effects, like hot flashes, fatigue, and sexual problems 3% [24]
16% [11]
54% [24]
Out-of-pocket cost Total out-of-pocket cost for treatment, including all doses, is $X/montha $5
$75
$200
$350

aThe levels of this attribute were not obtained from the literature, although they were evaluated in the cognitive interviews