Table 1 Glycans and protein ligands of siglecs in tumors

Siglec	Cell	Glycan ligand	Protein ligand	Reference
Siglec-7	NK, Mono, Macro, T	Disialyl-T, α2,3/6 sia	CD43, CD45, CD162/PSGL-1, MUC2, MUC5AC	[ 11, 12, 19– 21]
Siglec-9	NK, Mono, Neu, DC, TAM, T	sLex, sTn, α2,3 sia	ST-MUC1, MUC16, LGALS3BP	[ 19, 22– 28]
Siglec-10	TAM, T, NK,	α2,3/6 sia	CD24, CD52	[ 31– 33]
Siglec-15	BMDM	sTn, α2,3/6 sia	CD44, CD11b	[ 22, 35, 37, 38]