Table 2.
Classification of patients according to the cardiometabolic-based chronic disease model stratified by area deprivation index.a
| Low ADI Group |
Middle ADI Group |
High ADI Group |
P-value for difference |
P-value for trend |
|
|---|---|---|---|---|---|
| n | 718 | 181 | 64 | ||
| ABCD | <0.001 | <0.001 | |||
| Stage 0/stage 1a | 287 (40.9) | 38 (21.3) | 20 (31.2) | <0.001 | |
| Stage 2 | 13 (1.9) | 5 (2.8) | 2 (3.1) | 0.340 | |
| Stage 3 | 2 (0.3) | 0 (0.0) | 0 (0.0) | 0.441 | |
|
Stage 4 |
400 (57.0) |
135 (75.8) |
42 (65.6) |
<0.001 |
|
| DBCD | 0.03 | 0.005 | |||
| Stage 0 | 111 (19.9) | 13 (8.5) | 5 (9.4) | <0.001 | |
| Stage 1 | 114 (20.4) | 32 (20.9) | 13 (24.5) | 0.537 | |
| Stage 2 | 5 (0.9) | 1 (0.7) | 1 (1.9) | 0.691 | |
| Stage 3 | 6 (1.1) | 4 (2.6) | 0 (0.0) | 0.745 | |
| Stage 4 |
323 (57.8) |
103 (67.3) |
34 (64.2) |
0.061 |
|
| HBCD | 0.007 | 0.017 | |||
| Stage 0 | 88 (12.3) | 6 (3.3) | 2 (3.1) | <0.001 | |
| Stage 1 | 55 (7.7) | 19 (10.5) | 9 (14.1) | 0.044 | |
| Stage 2 | 51 (7.1) | 12 (6.6) | 3 (4.7) | 0.494 | |
| Stage 3 | 388 (54.0) | 101 (55.8) | 36 (56.2) | 0.620 | |
| Stage 4 |
136 (18.9) |
43 (23.8) |
14 (21.9) |
0.218 |
|
| LBCD | 0.817 | 0.372 | |||
| Stage 0 | 2 (0.5) | 0 (0.0) | 0 (0.0) | 0.399 | |
| Stage 1 | 11 (2.9) | 3 (2.5) | 0 (0.0) | 0.360 | |
| Stage 2 | 137 (36.3) | 41 (34.2) | 9 (25.0) | 0.209 | |
| Stage 3 | 172 (45.6) | 58 (48.3) | 21 (58.3) | 0.169 | |
| Stage 4 | 55 (14.6) | 18 (15.0) | 6 (16.7) | 0.756 |
Data are presented as n (%). Percentages pertain to the number of patients at a specified stage for the respective driver-ADI group. Statistically significant differences or trends are indicated in bold. Chi-squared test or Fisher exact test were used to test the differences of each CMBCD driver among the three ADI groups (p-value for difference), Spearman's rank test was used to test the trend of each CMBCD driver across the three ADI groups (p-value for trend), and Cochran-Armitage test was used to test each stage of each CMBCD driver across the three ADI groups (p-value for trend). ABCD stage 0 and stage 1 are combined since, at this time, there is no clear parameter to differentiate “normal” patients from patients with “risk.” Abbreviations: ABCD - adiposity-based chronic disease; DBCD - dysglycemia-based chronic disease; HBCD - hypertension-based chronic disease; LBCD - lipid-based chronic disease.