Table 3.
Concentrations of amyloid Aβ1-42, Aβ1-40, total tau protein phosphorylated tau protein (pT181), and amyloid Aβ1-42/Aβ1-40 ratio in cerebrospinal fluid immediately after external lumbar drainage placement (0`), after 36 hours, and after 72 hours of drainage
|
|
0` |
36 h |
72 h |
P
|
|||
|---|---|---|---|---|---|---|---|
| median | range | median | range | median | range | ||
| Aβ1-42 (pg/mL) |
144.47 |
42.86-1486.14 |
320.02 |
15.24- 1386.78 |
273.93 |
42.86-580.41 |
0.010 |
| Aβ1-40 (pg/mL) |
2531.05 |
341.13-14250.56 |
4181.17 |
1064.94-22197.72 |
4254.3 |
384.28-21188.43 |
0.027 |
| Aβ1-42/Aβ1-40 (pg/mL) |
0.08424 |
0.02381-0.22653 |
0.06166 |
0.00686-0.22069 |
0.05726 |
0.01927-0.23922 |
<0.911 |
| Total tau |
161.2 |
22.69-334.99 |
275.8 |
77.51-693.76 |
296.33 |
15.77-1027.10 |
<0.001 |
| Tau pT181 | 27.42 | 13.14-58.86 | 50.92 | 23.57-108.78 | 48.74 | 17.83-123.23 | <0.001 |