Table 2. Results of the heterogeneity test and the horizontal pleiotropy test.
| Outcome | Genes | MR_pleiotropy_test Q_P value | MR_heterogeneity P value |
|---|---|---|---|
| Pancreatic cancer (bbj-a-140) | RECQL | 0.89 | 0.49 |
| AP2B1 | 0.04 | 0.06 | |
| MVP | 0.70 | 0.33 | |
| EIF2AK2 | 0.84 | 0.78 | |
| BCAS1 | 0.83 | 0.31 | |
| ENO1 | >0.99 | 0.36 | |
| MCM6 | 0.32 | 0.78 | |
| PSEN1 | >0.99 | 0.75 | |
| XPO1 | >0.99 | 0.98 | |
| LYZ | 0.27 | 0.006 | |
| SEC14L2 | >0.99 | 0.70 | |
| PYGB | 0.18 | 0.06 | |
| CORO1C | >0.99 | 0.93 | |
| ACTR3 | 0.91 | 0.74 | |
| STAT1 | 0.92 | 0.04 | |
| SLC25A12 | >0.99 | 0.94 | |
| ATP8A1 | 0.99 | 0.43 | |
| PALLD | 0.56 | 0.005 | |
| ACTN4 | 0.98 | 0.81 | |
| CAP1 | >0.99 | 0.86 | |
| RAP1GAP2 | 0.64 | 0.46 | |
| MYH11 | >0.99 | 0.86 | |
| LCP1 | 0.92 | 0.07 | |
| KIF23 | 0.72 | 0.04 | |
| TMOD3 | 0.38 | 0.001 | |
| BRCA2 | 0.99 | 0.96 | |
| PML | 0.95 | 0.12 | |
| CDC42BPA | 0.99 | 0.18 | |
| RALB | 0.99 | 0.52 | |
| SCD5 | 0.47 | 0.009 | |
| CCNA2 | 0.97 | 0.75 | |
| ITGB1 | 0.90 | 0.36 | |
| ALB | >0.99 | 0.79 | |
| PSMD1 | >0.99 | 0.50 | |
| SPATS2L | 0.16 | 0.05 | |
| KIF13B | 0.81 | 0.47 | |
| ECI2 | 0.27 | 0.31 | |
| INF2 | 0.39 | 0.09 | |
| HSPA1B | 0.60 | <0.001 |
MR, Mendelian randomization.