TABLE 1.
TCR Vβ oligoclonality in the CD8+ T cells from HTLV-1-infected individualsa
| Patient | No. of:
|
Frequency of oligoclonal Vβ (%) | |
|---|---|---|---|
| Oligoclonal Vβ segments | Positive Vβ segments | ||
| HAM1 | 12 | 24 | 50.0 |
| HAM2 | 11 | 19 | 57.9 |
| HAM3 | 6 | 15 | 40.0 |
| HAM4 | 5 | 10 | 50.0 |
| AC1 | 2 | 20 | 10.0 |
| AC2 | 5 | 22 | 22.7 |
a
CD8+ samples that showed marked expansions of CDR3 segments of a certain length within the given Vβ were defined as oligoclonal by spectratyping analysis when a single peak contained >50% of the total area under the spectratype curve for that Vβ family.