Fig. 4.

Effects of common drugs on IDPs identified by SMR. a, Significant results with FDR <0.05 (SMR). The causal estimates are expressed as β values with 95% CI values. The width of the lines extending from the midpoint represent the 95% CI. Both unadjusted P values (SMR) and FDR (SMR) values are given. b, Schematic diagram of the brain cortical structures in lateral and medial views. c, Schematic diagram of the subcortical structures in coronal and sagittal section views. d, Schematic diagram of the white matter tracts in lateral and rear views.