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. 2024 Aug 21;10(17):e36616. doi: 10.1016/j.heliyon.2024.e36616

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — DEGs analysis. (A) Volcano plot displaying the DEGs (n = 333) based on the data from TCGA. Each dot annotates a gene, and the left and right parts represents the down-regulated and up-regulated DEGs, respectively. (B) Heatmap based on the top 20 up-regulated and down-regulated DEGs in tumor and normal tissue. (C) DEGs (n = 333) and Hubgene(n = 120) obtained by WGCNA were intersected to obtain 10 key genes. (D) Locations of the intersected PCD-related genes on the chromosome. The outermost circle in the figure is chromosome, the middle gene line represents the position of the gene on the chromosome, and the inner circle represents the DEGs, with red representing upregulation and blue representing downregulation.