Figure 6.

Cell-cell interaction analysis infers potential critical ligand-receptors associated with aged-induced osteoclastogenesis

See also Table S11.

(A) The cell-cell interactions between different cell populations inferred by cellchat.

(B) The top ligand-receptors predicted between different cell populations.

(C) Gene expression of different receptors across different cell populations.

(D) Signaling network that connects the inferred receptors and key transcription factors that modulate the aged-induced osteoclastogenesis. Red, green, and blue square indicate ligand-receptors, signature genes, and TFs, respectively.

(E) Shows the top 20 enriched pathways of genes in (D).