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. 2024 Apr 16;47(5):100721. doi: 10.1016/j.bj.2024.100721

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© 2024 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 6 — Ex vivo^99mTc-UCMSC-EVs distribution in spleen tissues. The expression of CD73 was unevenly distributed in the spleen. Uniform expression was found in the red pulp and concentrated expression was found in the white pulp. (a) Control mouse without ^99mTc-UCMSC-EVs injection. (b) The upregulated expression of CD73 and DAPI in the spleen of the ^99mTc-UCMSC-EVs-treated mouse. (c) The corresponding concentrated radioactivity signal by autoradiography in the spleen of the ^99mTc-UCMSC-EVs-treated mouse.