Figure 2.

FST alleviates kidney damage in DN mice. (a) Blood glucose levels were measured in mice (n = 6). (b) 24 h urine protein levels in mice in the control, DN, and FST intervention at different dose (5, 10, 20 mg/kg) groups. (c) Serum creatinine levels in mice in the control, DN, and FST intervention at different dose (5, 10, 20 mg/kg) groups. Data are expressed as means ± SD. n = 6. ∗∗∗p < 0.001 compared to vehicle. #p < 0.05 compared to DN. ##p < 0.01 compared to DN. ###p < 0.001 compared to DN. NC: normal control; M: DN model, STZ (50 mg/kg); FST-L: low dose of FST (5 mg/kg); FST-M: middle dose of FST (10 mg/kg); FST-H: high dose of FST (20 mg/kg).