TABLE 1.
Effect of simultaneous treatment of cells with IFN-γ and infection of cells with HPIV3 on the production of infectious virions
| Time (h) | Viral yield (PFU/ml) after treatmenta
|
|
|---|---|---|
| No IFN-γ | IFN-γ (100 U/ml) | |
| 24 | 1 × 105 | 1 × 105 |
| 48 | 1 × 106–1 × 107 | 1 × 106–1 × 107 |
| 72 | 5 × 106–1 × 107 | 5 × 106–1 × 107 |
a
HT1080 cells were infected with HPIV3 at an MOI of 1.0, and at the indicated times postinfection, the progeny virions released into the medium were tested on a monolayer of CV-1 cells for production of plaques.