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. 2024 Sep 14;14:21527. doi: 10.1038/s41598-024-72031-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — MITF correlates with oxidoreductase activities in multiple datasets. (A) Gene ontology analysis (DAVID followed by REVIGO, for details see Methods) of downregulated genes after MITF knockdown in MALME-3 M cells. (B) Gene functional classification using DAVID revealed that multiple gene sets involved in redox regulation are significantly enriched among genes downregulated after MITF knockdown. Abbreviation: MITF Microphthalmia-associated transcription factor.