Table 1.

Summary of the parameters for a general exchanging pool i when we conduct R_ex and AREX fitting: solute‐water exchange rate (k_i), solute concentration (f_i), transverse relaxation time (T_2,s), and solute resonance frequency offset (Δ).

		Amide	Guanidino	Free water	MT	NOE (− 3.5)
ks (s-1)	LB–UB	1–250	1–1000	–	1–100	1–30
fs (10−3)		0.1–10	1–50	–	10–400	10–100
T2,s (10−3 s)		0.1–10	0.1–10	20–100	0.01–0.3	0.1–10
Δ (ppm)		3.5	2	0	− 2.4	− 3.5