Table 2.
Pseudo-code of the Rex based method for Z-spectra fitting and decomposition.
| Define a set of LB and UB from Table 1, and start at the point x0 = LB + (UB − LB)/2 |
| The pixel-wise decompositions of Reff and Rex for CEST are solved by nonlinear fitting function (lsqnonlin) in MATLAB |
| Loop for Z-spectra of each pixel |
| { |
| compute Reff and Rex fitting parameters from Eqs. (2) and (3), respectively |
| compute Z-spectra of Rex-line-fit from Eq. (1) |
| } |
| Obtain fitting parameters and reconstruct the Rex imaging from Z-spectra of each pixel |