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. 2024 Sep 15;5(10):e711. doi: 10.1002/mco2.711

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© 2024 The Author(s). MedComm published by Sichuan International Medical Exchange & Promotion Association (SCIMEA) and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The cytotoxicity of ZYZ384 on different cell lines. (A) The structure of ZYZ384, (B) human liver cancer cell HepG2, (C) human liver cancer cell Huh7, (D) human normal liver cells LO2, (E) human pancreas adenocarcinoma Miapaca2, (F) human colon cancer cell HTC116, (G) human breast cancer cell MDA‐MB‐231, (H) human non–small‐cell lung cancer cell A549, (I) SMYD3 overexpression and ZYZ384 treatment on LO2. Data were expressed as mean ± SEM. ***: p < 0.001; **: p < 0.01 versus control, one‐way ANOVA analysis.