TABLE 1.

The binding affinity of small molecules to the target protein SMYD3.

Compd	R 2	K D (M)
SMI1/8a	0.953	7.80 E‐05
SMI3/8b	0.7514	4.47E‐05
SMI11/7a	0.9085	1.15 E‐04
SMI12/7c	0.5939	6.99 E‐06
SMI13/7b	0.7926	9.57 E‐05
SM20/4a	0.933	2.16E‐05
SM17/4b	0.4431	4.67E‐06
SM28/4c	0.8129	2.76E‐06
SM31/4d	0.8931	2.60E‐04
SM23/4e	0.9218	2.10E‐05
EPZ031686	0.9745	1.95E‐04
BCI‐121	0.9493	1.14E‐04