Table 4.

Changes in Retinal Arteriole and Venule Calibers with Increasing Diabetic Retinopathy Severity

	Nonproliferative Diabetic Retinopathy			Proliferative Diabetic Retinopathy (n = 42)	P Value (Overall)*	Model 1†
	Mild (n = 71)	Moderate (n = 65)	Severe (n = 107)
Arteriolar inner caliber	102.36±10.96	104.48±13.47	101.03±12.46	103.63±15.06	0.349	—
Venular inner caliber	123.39±13.55	126.07±14.32	128.45±15.67	130.38±15.32	0.055	—
Arteriolar outer caliber	133.20±28.38	116.43±26.61	111.15±26.13	117.83±33.85	<0.001	0.654
Venular outer caliber	114.48±8.23	117.28±10.54	117.86±12.26	123.27±17.84	0.003	<0.001

^*Kruskal-Wallis with pairwise comparisons. Caliber measurement in microns.

^†Correcting for correlation between 2 eyes, age, gender, type of diabetes mellitus, hypertension, spherical equivalent, hemoglobin A1c, alternate vessel caliber and P value Bonferroni adjusted for multiple analysis.