Fig. 5.

Impact of the elimination era on numbers of (a) decompensated cirrhosis and (b) hepatocellular carcinomas diagnoses, (c) liver-related mortality, and (d) all-cause mortality, among people with an HCV notification. Impact of the elimination era on numbers of (a) decompensated cirrhosis and (b) hepatocellular carcinomas diagnoses, (c) liver-related mortality, and (d) all-cause mortality, among people with an HCV notification. Data from individuals with an HCV notification in New South Wales, 1995–2022 (n = 112,277). (a) Decompensated cirrhosis diagnoses, (b) hepatocellular carcinoma diagnoses, (c) liver-related mortality and (d) all-cause mortality. Segmented Poisson regression models, fitting a second time trend parameter using splines, were used to evaluate the effect of the elimination era on the numbers of decompensated cirrhosis and hepatocellular carcinoma diagnoses, liver-related mortality, and all-cause mortality. DC, decompensated cirrhosis; HCC, hepatocellular carcinoma; HCV, hepatitis C virus.