Table 3.

Unadjusted and adjusted factors associated with liver-related mortality among people with an HBV notification.

Characteristics	Liver-related mortality n (%)	IRR	95% CI	p	aIRR	95% CI	p
Year of birtha
≥1967	250 (<1)	1.00	–	–	1.00	–	–
<1967	1408 (5)	7.39	6.46–8.44	<0.001	6.32	5.52–7.25	<0.001
Sex
Female	373 (1)	1.00	–	–	1.00	–	–
Male	1285 (4)	2.86	2.55–3.21	<0.001	2.28	2.04–2.57	<0.001
History of AUD
No	1447 (2)	1.00	–	–	1.00	–	–
Yes	211 (14)	6.08	5.31–6.96	<0.001	4.59	4.00–5.25	<0.001
Charlson comorbidity index 3+b
No	1487 (2)	1.00	–	–	1.00	–	–
Yes	171 (7)	2.86	2.45–3.33	<0.001	1.62	1.39–1.89	0.017
Elimination erac
No	1481 (3)	1.00	–	–	1.00	–	–
Yes	177 (1)	0.46	0.39–0.54	<0.001	0.68	0.59–0.80	<0.001

Unadjusted and adjusted factors associated with liver-related mortality among people with an HBV notification. Data from people with an HBV notification (n = 64,865) in New South Wales, 1995–2022.

Factors associated with liver-related mortality were evaluated using unadjusted and adjusted Poisson regression analyses. The adjusted model is based on 64,555 individuals. aIRR, adjusted incidence rate ratio; HCV, hepatitis C virus; IRR, incidence rate ratio; AUD, Alcohol use disorder.

^aStratified around median.

^bCharlson comorbidity index score is an indicator of health; higher scores indicate worse health condition.

^cElimination Era: Post 1 January 2015.