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. 2024 Aug 26;76:103328. doi: 10.1016/j.redox.2024.103328

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© 2024 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 10 — Targeting HERC1-NCOA4 axis enhances the antitumor effect of MPPα-PDT in vivo. (A) Fluorescence images in vivo after MPPα processing. (B) Quantitative analysis of fluorescence intensity at different time points. (C) Growth curves of tumors after different treatments. (D) Photographs of tumors harvested from mice after various treatments. (E) Gross tumor volume of tumors after different treatments. (F) Weight of tumors after different treatments. (G) The expression of Ki67, Cleaved caspase 3, and COX2 proteins detected by IHC. Scale bar: 50 μm. (H) The fluorescent images of TUNEL and lipid-ROS. Scale bar: 50 μm. Analyses were repeated in triplicate (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001.