Table 2.
Diagnostic criteria for CIM.
| All (n = 22) |
ICUAW− (n = 2)† |
ICUAW+ (n = 20)† |
CIM− (n = 10)† |
CIM+ (n = 12)† |
CIM− ICUAW+ (n = 8)† |
||
|---|---|---|---|---|---|---|---|
| Clinical criteria | (1) Critical illness | 22/22, 100 % | 2/2, 100 % | 20/20, 100 % | 10/10, 100 % | 12/12, 100 % | 8/8, 100 % |
| (2) Clinical weakness | 20/22, 92 % | 0/2, 0 % | 20/20, 100 % | 8/10, 80 % | 12/12, 100 % | 8/8, 100 % | |
| Electrophysiological criteria | (3–6) Combined | 12/22, 55 % | 0/2, 0 % | 12/20, 60 % | 0/10, 0 % | 12/12, 100 % | 0/8, 0 % |
| (3 & 4) NCS | 12/22, 55 % | 0/2, 0 % | 12/20, 60 % | 0/10, 0 % | 12/12, 100 % | 0/8, 0 % | |
| (5) EMG/Inexcitability | 15/22, 68 % | 0/2, 0 % | 15/20, 75 % | 3/10, 30 % | 12/12, 100 % | 3/8, 38 % | |
| (6) Repetitive Stimulation | 0/22, 0 % | 0/2, 0 % | 0/20, 0 % | 0/10, 0 % | 0/12, 0 % | 0/8,0 % | |
| Muscle biopsy | (7) M:A ratio | 0.76 (±0.28) | 0.71 (±0.033) | 0.77 (±0.29) | 0.88 (±0.35) | 0.66 (±0.19) | 0.93 (±0.35) |
Note. Data are reported as mean (±standard deviation) or absolute numbers (percentages). The diagnostic criteria for CIM are divided into clinical and electrophysiological criteria, and muscle biopsy. See Latronico and Bolton (2011) for a detailed description of the individual criteria. ICUAW, intensive care unit acquired weakness; CIM, critical illness myopathy; NCS, nerve conduction studies; EMG, electromyography; M:A ratio, myosin:actin ratio.
†
The sample sizes of the different sub-groups refer to the total sample size of all included patients (n = 22).