Table 1.

Plasma parameters

Parameter	WT Chow	WT HFD	SCD4−/− Chow	SCD4−/− HFD
Glucose [mg/dl]	174.0 ± 28.1	222.2 ± 25.4a	168.5 ± 31.8b	190.7 ± 23.8
Insulin [ng/ml]	1.5 ± 0.1	4.6 ± 0.2a	1.4 ± 0.1b	2.2 ± 0.5a,b,c
HOMA-IR index	17.9 ± 2.5	72.1 ± 10.9a	17.0 ± 1.3b	29.3 ± 6.5a,b,c
Cholesterol [mg/dl]	85.5 ± 8.3	149.1 ± 17.6a	71.5 ± 11.6a,b	123.8 ± 21.8a,b,c
Triglyceride [mg/dl]	130.9 ± 35.9	131.2 ± 28.2	113.5 ± 21.5	130.3 ± 25.4
Nonesterified fatty acids [mg/dl]	24.1 ± 7.3	20.9 ± 5.3	23.0 ± 6.0	22.3 ± 5.0

The data are expressed as mean ± SD, n = 10–12 mice/group.

^aP < 0.05, versus WT chow.

^bP < 0.05, versus WT HFD.

^cP < 0.05, versus SCD4^−/− chow.