Table 2.
Proportion and number of individuals with Lp(a) laboratory result ≤ 50 mg/dL, >50 mg/dL, >100 mg/dL and >180 mg/dL, and median (IQR) of Lp(a) in mg/dL.
| Roche assay |
Siemens assay |
||||
|---|---|---|---|---|---|
| Lp(a) threshold (mg/dL) | % (N) | Lp(a) (IQR)a | % (N) | Lp(a) (IQR)a | Ratiob |
| ≤ 50 | 78 (58,242) | 11.9 (6-22.1) | 82 (15,931) | 10 (10-17) | 1.0 |
| >50 | 22 (16,747) | 79.1 (63.6-106.8) | 18 (3,590) | 77.2 (62.2-102.2) | 1.2 |
| >100 | 6.6 (4,932) | 128.3 (111.9-152.7) | 4.9 (965) | 120.8 (108.3-140.9) | 1.3 |
| >180 | 0.72 (543) | 204.8 (188.8-231.1) | 0.40 (78) | 199.6 (190.3-221.4) | 1.8 |
Values in the respective groups in 2000-2009 (Roche assay, N = 74,989 individuals) and 2018 – 2019 (Siemens assay, N = 19,521) analyzed in serum samples.
Lp(a) = lipoprotein(a). IQR = inter quartile range.
a
Median (IQR) Lp(a) in mg/dL.
b
Ratio calculated by % individuals below or above Lp(a) thresholds in measurements analyzed by the Roche assay, divided by % individuals below or above Lp(a) thresholds in measurements analyzed by the Siemens assay.