Table 8.
Relative treatment effects (RTE) table for PGIC from the non-parametric longitudinal factorial analysis.
| Group | Time | Count | Rank Means | RTE | Bias | Variance | Lower | Upper |
|---|---|---|---|---|---|---|---|---|
| Placebo | BLa | 20 | 137.875 | 0.7632 | 1.00E-04 | 0.0282 | 0.717 | 0.8021 |
| Placebo | D30 | 20 | 127.975 | 0.7082 | 0.00E+00 | 0.0104 | 0.6815 | 0.7331 |
| Placebo | D60 | 20 | 115.325 | 0.6379 | −1.00E-04 | 0.0761 | 0.5649 | 0.7035 |
| AE120 | BL | 20 | 132.925 | 0.7357 | 0.00E+00 | 0.0255 | 0.6926 | 0.7734 |
| AE120 | D30 | 20 | 60.05 | 0.3308 | −1.00E-04 | 0.0164 | 0.2996 | 0.3642 |
| AE120 | D60 | 20 | 28.175 | 0.1538 | 1.00E-04 | 0.0188 | 0.1241 | 0.1941 |
| AE60 | BL | 20 | 130.45 | 0.7219 | 1.00E-04 | 0.0164 | 0.688 | 0.7528 |
| AE60 | D30 | 20 | 52.175 | 0.2871 | 1.00E-04 | 0.0207 | 0.2526 | 0.3253 |
| AE60 | D60 | 20 | 29.55 | 0.1614 | −2.00E-04 | 0.0526 | 0.1157 | 0.2344 |
a
BL: Baseline; RTE tending below 0.5 means that AE60 and AE120 were able to considerably reduce the PGIC scores whereas placebo can be seen with minimal change to the RTE. The systematic deviation of the estimated treatment effect from the true treatment effect is given as the bias. How much the estimated treatment effects vary across different samples or iterations of the analysis is given by the variance.