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. Author manuscript; available in PMC: 2024 Sep 16.
Published in final edited form as: Lancet Infect Dis. 2022 Dec 16;23(5):e167–e174. doi: 10.1016/S1473-3099(22)00641-7

Table 4:

Patient behaviours of 122 breakthrough rabies infections with and without deviations from core practices

Breakthrough infection with reported or possible deviation from core practices (n=68)* Breakthrough infection without deviation from core practices (n=54)*
N Median (IQR) N Median (IQR)
Time from exposure to wound care, days 8 0 (0–1) 39 0 (0–0)
Time from exposure to vaccine administration, days 61 1 (0–2) 54 0 (0–2)
Time from exposure to rabies immunoglobulin administration, days 25 0 (0–2) 39 0 (0–2)
Patient did not return for additional doses of vaccine 68 2 (3%) 54 0 (0%)

Data are N, median (IQR) range, or n (%).

*

Breakthrough infections without deviations in core practices were defined as those for which studies reported wound cleaning (regardless of wound cleaning thoroughness), studies did not indicate a concern with the injection site of rabies vaccines (ie, about incorrect administration into the gluteal muscle), and the current authors could determine that vaccine doses had been given according to a validated vaccine schedule. Breakthrough infections with known or possible post-exposure prophylaxis deviations included those with deviations or possible deviations from at least one of the core practices.

n (%).