Table 4:
Breakthrough infection with reported or possible deviation from core practices (n=68)* | Breakthrough infection without deviation from core practices (n=54)* | |||
---|---|---|---|---|
N | Median (IQR) | N | Median (IQR) | |
Time from exposure to wound care, days | 8 | 0 (0–1) | 39 | 0 (0–0) |
Time from exposure to vaccine administration, days | 61 | 1 (0–2) | 54 | 0 (0–2) |
Time from exposure to rabies immunoglobulin administration, days | 25 | 0 (0–2) | 39 | 0 (0–2) |
Patient did not return for additional doses of vaccine | 68 | 2 (3%)† | 54 | 0 (0%)† |
Data are N, median (IQR) range, or n (%).
Breakthrough infections without deviations in core practices were defined as those for which studies reported wound cleaning (regardless of wound cleaning thoroughness), studies did not indicate a concern with the injection site of rabies vaccines (ie, about incorrect administration into the gluteal muscle), and the current authors could determine that vaccine doses had been given according to a validated vaccine schedule. Breakthrough infections with known or possible post-exposure prophylaxis deviations included those with deviations or possible deviations from at least one of the core practices.
n (%).