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. 2024 Sep 2;15:1419527. doi: 10.3389/fimmu.2024.1419527

Table 1.

Clinically approved and licensed mucosal vaccines for use in humans.

Type Pathogen
(Disease)
Vaccine Administration
Route
Approval
year
References
Live-attenuated lnfluenza A/B viruses (Influenza) FluMist™ Intranasal 2003 (159)
Vibrio cholerae (Cholera) Vaxchora™ Oral 2015 (160)
Rotavirus (Diarrheal) RotaTeq™ Oral 2006 (161)
Rotarix™ Oral 2008 (161)
Salmonella typhimurium (Typhoid) Typhi Vivotif™ Oral 2013 (162)
Poliovirus (Polio) Oral polio vaccine (OPV™) Oral 1961 (163)
Inactivated Vibrio cholerae (Cholera) Dukoral™ Oral 2003 (164)
Shanchol™ Oral 2013 (165)
Euvichol™ Oral 2013 (165, 166)