Figure 1.

Pancreas regeneration is affected with aging. (A) Schematic representation of the experimental model to induce acute pancreatitis in young and old mice. (B) Representative H&E images of indicated conditions of young (left) and aged (right) mouse pancreas. Scale bars represent 100 μm. Arrows indicate infiltration (red) and apparent ADMs (black). (C) Quantification of ratio acinar area per tissue area in young and aged mice. At least 3 mice per group. Statistical analysis was determined by two-way analysis of variance. Error bars represent SD. Values of significance: ns P > .05 is omitted, ∗P ≤ .05, ∗∗∗P ≤ .001, ∗∗∗∗P ≤ .0001.