Table 2. SPR Data of 8 Validated Hits from Virtual Screening^a.

	Target
	HO-1		HO-2
Compd	Fit model	KD (nM)	Fit model	KD (nM)
2	Steady state	648	Steady state	N.D.
3	Steady state	5100	Steady state	N.D.
4	Steady state	141	Steady state	N.D.
5	Steady state	1420	Steady state	N.D.
6	Steady state	11000	Steady state	N.D.
6a	Steady state	7590	Steady state	N.D.
7	Steady state	9290	Steady state	N.D.
8	Steady state	794	Steady state	119

^aN.D. = binding not detected.