Fig. 2.

BHTD alleviated brain injury and repaired the blood–brain barrier. A Representative images of HE staining and IHC staining in brain (× 200, scale bar = 100 µm). B The average optical densities of Occludin, Claudin-1 and ZO-1 in brain. (n = 4) C Relative mRNA level of Occludin, Claudin-1 and Zo-1 in brain. (n = 6) D, E Serum levels of S-100B and NGB. F, G Brain levels of S-100B and NGB. D–G, n = 6) All data are shown as mean ± SD. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001