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. 2024 Sep 15;19:126. doi: 10.1186/s13020-024-00991-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Transplantation of BHTD-regulated gut microbiota relieved the symptoms of ischemic stroke. A The schematic diagram of the experimental procedure. B Relative body weight gain for 14 days. C Survival curve. D Longa score. E mNSS score. (A–D, n = 10) (F) Representative images of TTC staining. (G) Quantitative analysis of cerebral infarct areas (n = 4). H Representative images of Nissl (scale bar = 50 µm), HE (scale bar = 100 µm) staining in brain and colon tissues. I Quantification of the Nissl staining (n = 4). J Serum levels of S-100B. K Plasma levels of FD-4. L Serum levels of LPS. J–L, n = 6) All data are shown as mean ± SD. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.