Fig. 5.

Some typical applications of PepNzymes in analysis, diagnostics, and cellular imaging. (A) Nanozyme-linked immunosorbent assay using peptide-conjugated gold nanoprobes for integrin expression on cell membranes. Reproduced with permission from Ref. [40], copyright 2015, American Chemical Society. (B) Copper nano-assemblies regulated by peptides for trypsin assays and inhibitor screening. Reproduced with permission from Ref. [93], copyright 2022, American Chemical Society. (C) Gold nanoparticles mineralized by peptide liquid crystals with dual-functional enzyme-like activities for glucose detection. Reproduced with permission from Ref. [94], copyright 2023, American Chemical Society. (D) Plasmon-mediated peroxidase activity on asymmetric nanotubes with FITC-peptides for rapid visual bacteria detection. Reproduced with permission from Ref. [95], copyright 2022, American Chemical Society. (E) Fluorenylmethoxycarbonyl-arginine-glycine-aspartate/hemin nanoparticles for cancer cell detection and inhibition of TGF-β-induced EMT in breast cancer cells. Reproduced with permission from Ref. [97], copyright 2019, American Chemical Society.