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MTAP Immunostaining Versus PD-L1 Immunostaining and CD8+ T-cell Density
| PD-L1 positive (% of tumors) | CD8+ density (cells/mm2) | |||||
|---|---|---|---|---|---|---|
| MTAP status* | n | Tumor cells | n | Immune cells | n | Mean±SE |
| Loss | 559 | 19.9 | 61.9 | 321 | 179.2±28.2 | |
| Retained | 7262 | 15.7 | 71.8 | 3915 | 263.3±8.1 | |
| P | — | 0.0125 | 0.0008 | — | 0.0042 | |
MTAP loss: no MTAP immunostaining, MTAP retained: MTAP 1+ to 3+ immunostaining.
