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. 2005 May 26;102(23):8275–8280. doi: 10.1073/pnas.0408589102

Fig. 3.

Fig. 3.

Growth kinetics of HCoV-229E in vitro. (A) PEFs from the indicated transgenic mice or MRC-5 cells were infected (multiplicity of infection = 1) with HCoV-229E grown in MRC-5 cells at 32°C. (B) PEFs from hAPN+/+Stat1+/+ (a and b) and hAPN+/+Stat1-/- (c and d) mice were infected (multiplicity of infection = 1) with HCoV-229E or HCoV-229E-37, respectively. In A and B, infected cells were incubated at 32°C (a and c) or 37°C (b and d) for the indicated times. Virus growth was evaluated by determining the plaque forming units in swine testis-hAPN cells.