Fig. 1.

Models of nucleosome and linker DNA. (a Left) Crystal structure of nucleosome with complete modeled histone tails (PDB ID code 1KX5). (a Right) DiSCO model of the nucleosome with 300 effective charges located on an irregular surface. The surface was reduced by5Åto show the positions of the charges. The color scale indicates the value of each charge in the unit of e. (b Left) Linker DNA that connects two nucleosomes. (b Right) DNA bead model with six beads of 3-nm diameter. (c) Simplified representation of a short nucleosomal array showing how linker DNA connects nucleosomes.