TABLE 1.

Protein composition of HSV-1 B capsid^a

Measurement	VP5	75-kDa protein	UL25	VP19C	VP21	VP22a	VP23	VP24	VP26
Mol wt	149,075	75,000	62,666	50,260	45,000	33,765	34,268	26,618	12,095
Fraction (%, wt/wt)b	52.6 ± 3.4	1.5 ± 0.3	1.2 ± 0.4	8.2 ± 0.9	2.4 ± 0.9	13.9 ± 1.1	10.8 ± 3.5	2.2 ± 0.9	5.7 ± 1.6
Corr.fc	58.4	1.3 ± 0.3	1.1 ± 0.4	7.2 ± 0.8	2.1 ± 0.8	12.2 ± 1.0	9.5 ± 3.1	1.9 ± 0.8	5.0 ± 1.4
Copy no.d	960	44 ± 13	42 ± 17	351 ± 38	114 ± 44	885 ± 70	679 ± 223	175 ± 76	1,013 ± 282

^aProteins stained by Coomassie brilliant blue in lane 3 of Fig. 1B were scanned in a densitometer, and a quantitative determination was made using National Institutes of Health Image software. Values are the means ± standard deviations for nine independent measurements in B capsids. 

^bFraction of total protein. 

^cCorr.f, corrected percentages calculated assuming that B capsid contains 960 copies of VP5. 

^a Copy numbers (N) were calculated from the capsid masses (245 MDa [37]), the corrected percentages (Coff.f), and molecular masses (m) of each capsid, as follows: N = (245 Corr.f/m) × 10⁶.