TABLE 2.

QSAR analysis, best correlations, and used descriptors of the regression analysis

Antimicrobial activity	r2	F value	r2 (cv)	Descriptors
All compounds
Log(1/MICE. coli)	0.70	8.23	0.28	Kier flexibility, NNmin
Log(1/MICS. aureus)	0.69	7.84	0.33	Avg structural information content (order 2), relative no. of rings
Log(1/ENC50)	0.72	8.81	0.36	Avg information content (order 1), no. of O atoms
Only compounds 1-7
Log(1/MICE. coli)	0.93	26.5	0.78	NNmin, ZX shadow
Log(1/MICS. aureus)	0.96	50.0	0.92	Avg information content (order 2), ZX shadow/ZX rectangle
Log(1/ENC50)	0.98	88.6	0.92	YZ shadow/YZ rectangle, Balaban index