Table 1.
Diagnostic accuracy of the objective pupillometer in diagnosing RAPD, vis-à-vis, clinical judgments of the study participants.
| Youden’s cut-off | Area under ROC curve | Sensitivity (%) |
Specificity (%) |
Accuracy (%) |
Precision (%) |
MCC | |
|---|---|---|---|---|---|---|---|
| Overall (n=77) | 1.17 | 0.87 | 78.5 | 87.0 | 82.7 | 85.7 | 0.66 |
| Mild RAPD (n=50) | 1.17 | 0.81 | 68.0 | 92.0 | 80.0 | 89.5 | 0.62 |
| ≥Moderate RAPD (n=27) | 1.50 | 0.97 | 89.1 | 96.3 | 92.6 | 96.0 | 0.85 |
| Re-organized (n=77) | 1.17 | 0.91 | 85.1 | 89.7 | 87.7 | 85.3 | 0.75 |
These outcome variables were obtained following a standard ROC analysis. Data of ROC curves obtained using the overall data (second row), only for cases with mild RAPD (third row), only for cases with moderate or higher severities of RAPD (fourth row) and controls data re-organized (last row) are shown in this table. MCC: Matthews Correlation Coefficient (31).