Table 3.

Outcomes of patients.

Outcomes	Intervention group (N = 619)	Control group (N = 619)	P
Primary outcome
28-day mortality, no. (%)	133 (21.5)	168 (27.1)	0.020
Secondary outcomes
LOS [median (IQR)], days
In ICU	5.92 [3.64, 10.92]	5.04 [3.23, 9.23]	0.001
In hospital	12.36 [7.86, 20.46]	11.29 [6.81, 18.62]	0.018
28-day cumulative mechanical ventilation–free days [median (IQR)], days	26.23 [22.23, 27.54]	26.60 [23.42, 28.00]	0.002
28-day cumulative vasoactive agent–free days [median (IQR)], days	26.75 [24.95, 27.56]	26.10 [24.30, 27.17]	<0.001
28-day cumulative RRT–free days [median (IQR)], days	28.00 [28.00, 28.00]	28.00 [28.00, 28.00]	0.685

Data are presented as mean ± SD or median (interquartile range) for skewed variables or proportions for categorical variables.

LOS, length of stay; IQR, interquartile range; ICU, intensive care unit; RRT, renal replacement therapy.