TABLE 1.

MICs and MBCs of citropin 1.1 and other clinically used antibiotics for 90 clinical isolates

Strains (n) and agent	MIC (mg/liter)			MBC (mg/liter)
	Range	50%	90%	Range	50%	90%
MR S. aureus (20)
Citropin 1.1	1-16	4	8	2-32	8	16
AMX/CLVa	2-128	16	128	8-128	64	256
Doxycycline	0.50-16	4	8	2-64	8	32
Clarithromycin	0.50-16	4	16	2-128	32	128
Linezolid	0.25-4	0.5	2	0.50-2	0.5	2
Vancomycin	0.12-4	1	2	0.50-4	1	2
MS S. aureus 20
Citropin 1.1	1-16	4	8	2-16	8	16
AMX/CLVa	0.25-8	2	4	0.5-32	8	16
Doxycycline	0.50-8	4	8	2-32	8	32
Clarithromycin	0.50-16	2	8	2-64	16	64
Linezolid	0.12-2	0.5	2	0.50-2	0.5	2
VS Enterococcus faecalis 30
Citropin 1.1	2-32	8	16	2-32	16	32
AMX/CLVa	1-64	8	16	4-256	16	64
Doxycycline	1-32	8	16	4-128	16	64
Clarithromycin	4-128	8	32	8-256	16	128
Linezolid	0.50-4	1	2	0.5-4	2	4
Vancomycin	0.25-4	1	2	1-4	2	4
VR Enterococcus faecalis 12
Citropin 1.1	2-32	8	16	2-64	16	32
AMX/CLVa	4-128	16	32	8-256	64	128
Doxycycline	2-64	16	32	8-64	16	64
Clarithromycin	8-128	16	64	16-256	32	128
Linezolid	0.50-4	1	2	1-4	4	4
Vancomycin	32-128	32	64	64-256	64	256
Streptococcus pyogenes 20
Citropin 1.1	1-8	2	4	2-16	4	8
AMX/CLVa	0.25-2	0.50	1	0.5-4	1	4
Doxycycline	0.50-8	4	8	1-32	8	16
Clarithromycin	0.50-8	2	8	1-32	8	32
Linezolid	0.12-2	0.5	1	0.50-2	1	2
Vancomycin	0.25-2	0.5	1	0.50-2	1	2

^aAMX/CLV, amoxicillin-clavulanate, ratio 7:1.