Fig. 4. Levels of pS129-αSyn in the CSF of patients with detectable CSF antibodies after immunization with UB-312.

CSF samples were analyzed in duplicate using immunomagnetic reduction as described in the methods, in patients with (n = 5) and without (n = 13) detectable CSF antibody titers. Data are expressed as percent CFB, mean ± s.e.m. A Bonferroni multiple comparisons test confirmed a significant difference between groups at EoS, *P = 0.0154.