FIG. 2.

Poly(I:C₁₂U) induction of alpha/beta interferon in hamsters. poly(I:C₁₂U) (4 or 0.4 mg/kg) or loxoribine (80 or 8 mg/kg) was injected i.p. into 7-week-old hamsters and serum was collected after 2 h. Values are represented as percentages of NR uptake of control CHO-K1 cells and are a measure of the ability of diluted serum samples (triplicate) to protect cells from VSV-induced cytotoxicity. Interferon alfacon-1 (200 ng/ml) was included as a positive control and diluted as indicated.