Skip to main content
. 2024 Apr 6;31(9):1323–1334. doi: 10.1038/s41417-024-00766-8

Fig. 6. Cytokine secretion of Fn14-redirected RevCAR NK-92 cells.

Fig. 6

The pro-inflammatory cytokine IFN-γ was detected using ELISA in supernatants from co-culture experiments of either U251 Luc or U343 Luc cells with either (A) RevCAR-E5B9 or (B) RevCAR-E7B6 NK-92 cells incubated at an E:T ratio of 10:1, 5:1 or 2:1 in the absence or presence of either matching Fn14-specific RevTM or irrelevant one (negative control) for 4 h. Results are shown as mean ± SD for three independent experiments. (One-way ANOVA with Tukey multiple comparison test, *p < 0.0332, **p < 0.0021, ***p < 0.0002, ****p < 0.0001; comparison to samples without RevTM or with irrelevant RevTM).