FIG. 1.

Structural organization of the JCV genome and Agno protein. (A) JCV genomic structure, depicting the direction of the genes encoding the early and late proteins with arrows. Early genes encode small and large T antigens. Late genes encode viral capsid proteins, VP-1, -2, and -3, and Agno protein. The control region is located between the early and late genes. (B) Comparison of primary amino acid sequences of JCV Agno protein with its counterparts from SV40 and BKV.