FIG. 6.

Analogues of tiazofurin. All compounds were obtained from the Drug Development and Clinical Sciences Branch of the National Institute of Allergy and Infectious Diseases (Mohamed Nasr). A commercial preparation of tiazofurin was also tested. Tiazofurin is 2-β-d-ribofuranosylthiazole-4-carboxamide; Se-tiazofurin is 2-β-d-ribofuranosylselenazole-4-carboxamide; TAD is thiazole-4-carboxamide adenine dinucleotide; β-methylene TAD is 4-carboxamido-2-β-d-ribofuranosylthiazolyl adenosine methylenediphosphonic acid; β-methylene SAD is 4-carboxamido-2-β-d-ribofuranosylselenazolyl (5′ + 5′) adenosine methylenediphosphonic acid.