Table 2.

Treatment outcomes of ER

	< 64 years	65–74 years	> 75 years	p-value
	n = 49	n = 51	n = 50
Lesions
Size, median (IQR), mm	19 (12–27)	20 (11–28)	20 (11–28)	0.555
Location (Ce/Ut/Mt/Lt)	0/3/31/15	0/6/38/7	2/4/39/5	0.048
Macroscopic type (elevated/flat/depressed)	4/24/21	5/22/24	4/24/22	0.813
EMR/ESD	5/44	11/40	9/41	0.479
En bloc resection rate, %	95.9	94.1	98	0.794
Invasion depth, n (%)
Pre-operative diagnosis depth, n (%)				0.409
EP	19 (38.8)	20 (39.2)	16 (32)
LPM	26 (53.1)	23 (45.1)	24 (48)
MM/SM1	4 (8.2)	8 (15.7)	10 (20)
Pathological diagnosis depth, n (%)				0.367
EP	17 (34.7)	22 (43.1)	16 (32)
LPM	24 (49.0)	20 (39.2)	21 (42)
MM	5 (10.2)	6 (11.8)	9 (18)
SM1	2 (4.1)	3 (5.9)	2 (4)
SM2	1 (2.0)	0	2 (4)
Lymphovascular invasion, n (%)	2 (4.1)	0	2 (4)	0.538
Vascular invasion, n (%)	2 (4.1)	1 (2.0)	5 (10)	0.325
Horizontal margin, n (%)	5 (10.2)	0	4 (8)	0.149
Vertical margin, n (%)	2 (4.1)	2 (3.9)	2 (4)	0.997

Patients	< 64 years	65–74 years	> 75 years
	n = 41	n = 46	n = 40
Adverse events, n (%)	4 (8.2)	3 (5.7)	3 (6.0)	0.852
Stenosis, n (%)	3 (7.3)	0	2 (5.0)	0.200
Perforation, n (%)	1 (2.4)	0	1 (2.5)	0.564
Pneumonia, n (%)	0	1 (2.2)	0	0.415
Mediastinal emphysema, n (%)	0	2 (3.3)	0	0.169
Length of hospital stay for ER, median (IQR), days	7 (7–8)	7 (7–9)	7 (7–8)	0.622
Endoscopic interval, median (IQR), months	6 (6–6)	6 (6–7)	6 (6–6)	0.210

Ce cervical esophagus, EMR endoscopic mucosal resection, EP epithelium, ER endoscopic resection, ESD endoscopic submucosal dissection, IQR interquartile range, LPM lamina propria muscle, Lt Lower thoracic esophagus, MM muscularis mucosae, Mt middle thoracic esophagus, SM submucosal layer, Ut upper thoracic esophagus