Table 3.

Associations between coffee and tea consumption and overall survival after a diagnosis of ovarian cancer.

			None	<1 cup/day	1–2.49 cups/day	≥ 2.5 cups/day
	Modela	Nb	Reference	HR (95% CI)	HR (95% CI)	HR (95% CI)	P-trendc
Coffee	1	5713	1.0	0.93 (0.83–1.04)	0.97 (0.88–1.08)	0.99 (0.89–1.10)	0.8
	2	5688	1.0	0.93 (0.83–1.04)	0.97 (0.88–1.07)	0.97 (0.87–1.08)	0.8
Caffeinated	1	4108	1.0	0.93 (0.83–1.05)	0.94 (0.84–1.05)	1.00 (0.89–1.12)	0.97
	2	4096	1.0	0.94 (0.83–1.05)	0.93 (0.83–1.05)	0.99 (0.88–1.10)	0.8
Decaffeinatedd	1	4108	1.0	1.05 (0.94–1.17)	0.97 (0.85–1.10)	–	0.9
	2	4096	1.0	1.07 (0.96–1.20)	0.97 (0.85–1.11)	–	0.9
Black tea	1	5707	1.0	0.95 (0.87–1.04)	0.93 (0.83–1.04)	1.00 (0.89–1.11)	0.8
	2	5682	1.0	0.96 (0.88–1.05)	0.95 (0.85–1.06)	1.02 (0.91–1.14)	0.8
Green tead	1	2938	1.0	0.92 (0.83–1.03)	0.84 (0.71–0.99)	–	0.02
	2	2926	1.0	0.94 (0.84–1.06)	0.84 (0.71–1.00)	–	0.04
Herbal tead	1	2206	1.0	0.98 (0.86–1.11)	0.99 (0.81–1.21)	–	0.8
	2	2201	1.0	1.03 (0.90–1.17)	1.02 (0.83–1.25)	–	0.7
Total caffeinee	1	5408	1.0	0.99 (0.90–1.09)	0.94 (0.85–1.04)	1.05 (0.95–1.16)	0.5
	2	5388	1.0	0.99 (0.90–1.09)	0.94 (0.85–1.04)	1.03 (0.93–1.14)	0.8

^aModel 1: Hazard ratios (HR) and 95% confidence intervals (CI) adjusted for age and stratified by study, stage and histotype; Model 2 additionally adjusted for race, education, smoking, BMI and physical inactivity.

^bSee Table 1 for studies contributing to each model.

^cAssessed by assigning each level a number from 0 (Q1) to 3 (Q4) and modelling this as continuous variable.

^dThe top two groups were combined ( ≥ 1 cup/day) as few individuals drank more than 2.5 cups/day.

^eModelled in quartiles from lowest to highest.