Table 3.
Univariate and multivariate logistic analyses depicting the association of aneuploidy occurrence with basal FSH levels, maternal BMI, number of oocytes recovered, maternal age and FSH total dose in embryos grouped according to maternal age
| Overall | Pre-AMA (< 35 years) | AMA (≥ 35 years) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariate | Univariate | Multivariate | Univariate | Multivariate | |||||||
| OR (95% IC) | p | OR (95% IC) | p | OR (95% IC) | p | OR (95% IC) | p | OR (95% IC) | p | OR (95% IC) | p | |
| Basal FSH (high vs. low) | 1.02 (1.01–1.04) | < 0.0 | 1.02 (1.00–1.04) | 0.03 | 1.08 (1.01–1.15) | 0.03 | 1.08 (1.00–1.16) | 0.04 | 1.02 (1.00–1.04) | 0.03 | 1.01 (0.99–1.03) | 0.22 |
| Maternal BMI | 1.03 (1.00–1.07) | 0.07 | 1.02 (0.98–1.06) | 0.26 | 0.91 (0.83–1.01) | 0.08 | 0.93 (0.84–1.03) | 0.18 | 1.05 (1.01–1.09) | 0.01 | 1.02 (0.98–1.06) | 0.46 |
| N. oocytes | 0.97 (0.96–0.98) | < 0.0001 | 0.99 (0.98–1.01) | 0.34 | 1.00 (0.97–1.03) | 0.87 | ___ | ___ | 0.97 (0.96–0.99) | < 0.0001 | 0.99 (0.97–1.01) | 0.23 |
| Maternal age | 1.19 (1.15–1.23) | < 0.0001 | 1.18 (1.14–1.22) | < 0.0001 | 1.04 (0.96–1.14) | 0.33 | ___ | ___ | 1.38 (1.31–1.45) | < 0.0001 | 1.34 (1.26–1.43) | < 0.0001 |
| Total FSH | 1.00 (1.00–1.00) | 0.12 | ___ | ___ | 1.00 (1.00–1.00) | 0.78 | ___ | ___ | 1.00 (1.00–1.00) | 0.18 | ___ | ___ |
Note: High and low basal FSH values are those higher and lower than the group median, respectively